Sweet orange is a fruit. The peel and juice are used to make medicine. The peel of sweet orange is used to increase appetite; reduce phlegm; and treat coughs, colds, intestinal gas (flatulence), acid indigestion (dyspepsia), and cancerous breast sores. It is also used as a tonic. Sweet orange juice is used for treating kidney stones (nephrolithiasis) and high cholesterol; and preventing high blood pressure and stroke, as well as prostate cancer.