SAMe (pronounced "sammy") is short for S-adenosyl-L-methionine or S-adenosyl-methionine, a natural molecule formed in the body by methionine and adenosyl-triphosphate (ATP). Supplemental SAMe helps to raise serotonin, dopamine, and phosphatidylserine levels.

Studies have shown that SAMe positively influences mood and behavior, and works in conjunction with vitamin B12 and folic acid in our systems to encourage the healthy functioning of the brain. Along with its mood boosting properties, SAMe supports healthy joints by helping the body produce glucosamine and chondroitin. Natural Factors SAMe is formulated for high stability and coated to make it simple to swallow. Warning: People taking prescription antidepressants or who have been diagnosed with bipolar disorder should use this product only with a doctor's supervision.


  • Helps raise serotonin, dopamine, and phosphatidylserine levels
  • Without the side effects of perscription antidepressants
  • Support for arthritic disorders
  • Helps promote bile flow and inactivate excess estrogens


Serving size 1 Tablet
Serving: 30
Serving Quantité par portion
Ion S-adenosyl-L-methionine 200 mg **
(from 400 mg of SAMe Disulfate tosylate)  
**Daily value not established.  
Other Ingredients: dibasic calcium phosphate dihydrate, Vegetarian
capsule (carbohydrate gum [cellulose], purified water),
magnesium stearate (for vegatable quality)


Suggested use:

1 tablet on an empty stomach, 2 times per day for 3 weeks; then 1 tablet per day thereafter, or as directed by a health professional.


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